The Philosopher's Stone is the goal of all Alchemists. It is a legendary substance said to be capable of turning mercury into gold (or in some tales silver) In alchemy, the alchemical term for this process is chrysopoeia which literally means transmutation into gold, the Chrysopoeia is taken from the Greek words for "gold" (χρυσός, 'khrusos',) and "to make" (ποιεῖν, 'poiein'). It is also used to symbolically indicates the creation of the eponymous philosopher's stone and the completion of the Great Work.
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Philosopher's Stone Symbol
Philosopher's Stone in Marvel Comics
Philosopher's Stone in DC Comics
Philosopher's Stone in Aladdin: The Animated Series
Philosopher's Stone in Justice League
Philosopher's Stone in Harry Potter and the Philosopher's Stone (2001)
Philosopher's Stone in The Librarian: Curse of the Judas Chalice
Philosopher's Stone in Fullmetal Alchemist
Philosopher's Stone in Warehouse 13
Philosopher's Stone in As Above, So Below (2014)
Philosopher's Stone in The Flash
Philosopher's Stone in Sleepy Hollow